The most important update to NBA 2K22 MT the next generation version is the "City of Basketball" in the"MC" mode. It is the "City of Basketball" in NBA 2K22 is now available in the community mode in 2K18 19. Incorporating the main storyline into the huge "Basketball City" players must increase their market share through activities like music and fashion trends along with their basketball career. To become an NBA player with a comprehensive growth of intelligence, morality physicality, art and labor.

The plot of this game is still the familiar game plot used in it's 2K series. The AI Junior DJ and other characters used by players of earlier generations have also been transformed into NPCs in the game. The plot of the story is extensive, but the IQ of the script interpretation is a bit erratic, and the majority of plots do not have logic. This is embarrassing to the career model, which is based on substituting.

The endorsements for players in NBA 2K22 are divided into 10 brand attributes. Players build up brand attribute levels through various plot-related tasks such as NBA MT Coins community activities, plot tasks, and post-match interviews. Only after they have a sufficient amount of supporters and the brand attribute level will they be able to obtain the appropriate endorsement certificates.